MedChem Paper of the Month – May 2025
MedChemica2025-07-25T08:33:11+00:00Efficient Crystallization of Apo Sirt2 for Small-Molecule Soaking and Structural Analysis of Ligand Interactions
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Comp Chem Paper of the Month – May 2025
MedChemica2025-07-25T08:33:26+00:00Exploration of structure-activity relationships for the SARS-CoV-2 macrodomain from shape-based fragment linking and active
ACSMEDI-EFMC Medicinal Chemistry Frontiers – May 2025
MedChemica2026-06-17T13:44:05+00:00Summary of the ACSMEDI-EFMC Medicinal Chemistry Frontiers in May 2025 In May, we had
MedChem Paper of the Month – Apr 2025
MedChemica2025-07-25T08:33:35+00:00Cheminformatic Analysis of Core-Atom Transformations in Pharmaceutically Relevant Heteroaromatics J. Med. Chem., 2025, 68, 6,
8th RSC-BMCS / SCI Symposium on Ion Channels as Therapeutic Targets – April 2025
MedChemica2026-06-17T13:44:28+00:00Summary of 8th RSC-BMCS / SCI Symposium on Ion Channels as Therapeutic Targets –
Comp. Chem. Paper of the Month – Mar 2025
MedChemica2025-07-25T08:33:55+00:00Quantum Chemical Evaluation and QSAR Modeling of N-Nitrosamine Carcinogenicity N-Nitrosamines (compounds containing the R2N-N=O
BMCS 2nd Conformational Design in Drug Discovery – Mar 2025
MedChemica2026-06-17T13:44:57+00:00Summary of BMCS 2nd Conformational Design in Drug Discovery Conference 2025 Monday 3rd March
MedChem Paper of the Month – Mar 2025
MedChemica2025-07-25T08:34:03+00:00Discovery of 6‐Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4- dihydroquinoxalin-6 yl)methyl]piperazin-1-yl}‐N‐methylpyridine-2- carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor J. Med. Chem.,
MedChem Paper of the Month – Feb 2025
MedChemica2025-07-25T08:34:13+00:00A covalent chemical probe for Chikungunya nsP2 cysteine protease with anti-alphaviral activity and proteome-wide selectivity Sci.
Comp. Chem. Paper of the Month – Feb 2025
MedChemica2025-07-25T08:34:21+00:00Real-World Applications and Experiences of AI/ML Deployment for Drug Discovery After listening to Rob
