Data Exploration
SARkush®
Automated SAR Analysis via Markush-like Structures
SARkush® aids structure activity relationship (SAR) analysis of compound datasets by automatically clustering compounds into Markush-like (SARkush) structures.
A module within the MCPairs platform.
How SARkush® Works
SARkush® in three steps
Input File
Submit a file with compounds and data.
Prepare Search
Submit job or refine settings further for pair finding and clustering.
Review Results
Automatically downloads results and displays them in a grid form with R-group decomposition.
Why use SARkush®?
Key Benefits
Summarise Project Data
Automatically clusters compounds based on Matched Molecular Pair (MMP)-networks and generic-atom scaffolds, and generates Markush-like depictions and decomposition tables.
In-Depth Analysis
Speed up patent filing and reduce transcription errors. Analyse competitor patents.
Deeper Modelling
Use the output for further computational models (Free-Wilson, QSAR, etc.).
Desymmetrised Ring
Ensure similar R-groups are reported the same way to add clarity and consistency.
Web-based Access
Access SARkush® through MCPairs Online from any modern web browser—no software installation required.
