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So far jacqui has created 2 blog entries.

Comp. Chem. Paper of the Month – Feb 2023


    A Review of Computational Approaches Targeting SARS-CoV-2 Main Protease to the Discovery of New Potential Antiviral Compounds   Current Topics in Medicinal Chemistry, 2023, 23, 3-16   For this month’s computational chemistry paper of the month, we have chosen to highlight a recent review of the computational approaches used to identify inhibitors of

Comp. Chem. Paper of the Month – Feb 20232023-02-22T15:19:14+00:00

Beyond Rule of Five – A MedChemica Review


Recent bRo5 publications Figure 1: Picture summarising the limitations of obeying the Ro5 and the versatility obtained by going beyond (www.sciencedirect.com/science/article/abs/pii/S1367593117300480?via%3Dihub). Cast our minds back... It’s been more than 25 years since a Pfizer chemist: Christopher Lipinski, published1 his influential analysis of the calculated physical properties of a set of candidate drugs, leading to the well-known

Beyond Rule of Five – A MedChemica Review2023-02-22T08:36:24+00:00
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