Griffen EJ, Boulet P, ASAP Discovery Center and COVID Moonshot. Enabling equitable and affordable access to novel therapeutics for pandemic preparedness and response via creative intellectual property agreements [version 1; peer review: 3 approved]. Wellcome Open Res 2024, 9:374 (https://doi.org/10.12688/wellcomeopenres.22645.1)

Strategies to Mitigate CYP450 Inhibition From the book: The Medicinal Chemist’s Guide to Solving ADMET Challenges Alexander G. Dossetter, Marcel J. de Groot and Sarah E. Skerratt https://pubs.rsc.org/en/content/chapter/bk9781788012270-00220/978-1-78801-227-0

Small molecule Son of Sevenless 1 (SOS1) inhibitors: a review of the patent literature Severin K. Thompson, Andreas Buckl, Alexander G. Dossetter, Ed Griffen & Adrian Gill Expert Opinion on Therapeutic Patents, 31(12), 2021, 1189-1204.  A comprehensive review of the patent published with claims for SOS1 inhibitors. An analysis of the spread of simple properties

Mapping Ligand-Shape Space for Protein–Ligand Systems: Distinguishing Key-in-Lock and Hand-in-Glove Proteins Joanna Zarnecka, Iva Lukac, Stephen J. Messham, Alhusein Hussin, Francesco Coppola, Steven J. Enoch, Alexander G. Dossetter, Edward J. Griffen, and Andrew G. Leach*  J. Chem. Inf. Model. 2021, 61, 4, 1859–1874 March 23, 2021 https://doi.org/10.1021/acs.jcim.1c00089

Edward J. Griffen*, Alexander G. Dossetter, and Andrew G. Leach J. Med. Chem. 2020, 63, 16, 8695–8704 Publication Date:May 27, 2020 https://doi.org/10.1021/acs.jmedchem.0c00163

AI, Big Data and the Medicinal Chemist, Ed Griffen Linked-In Post, May 2018 https://www.linkedin.com/pulse/ai-big-data-medicinal-chemist-ed-griffen/

Edward J.Griffen, Alexander G.Dossetter, Andrew G.Leach, Shane Montague, Can we accelerate medicinal chemistry by augmenting the chemist with Big Data and artificial intelligence? Drug Discovery Today, online 22 March 2018 https://doi.org/10.1016/j.drudis.2018.03.011  

58) Data-mining patent literature for novel chemical reagents for use in medicinal chemistry design Jason G. Kettle, Richard A. Ward and Ed Griffen Med. Chem. Commun., 2010,1, 331-338.

59) WizePairZ: A Novel Algorithm to Identify, Encode, and Exploit Matched Molecular Pairs with Unspecified Cores in Medicinal Chemistry Daniel J. Warner, Edward J. Griffen and Stephen A. St-Gallay J. Chem. Inf. Model., 2010, 50 (8), pp 1350–1357 Publication Date (Web): August 6, 2010 (Article) DOI: 10.1021/ci100084s