Rationally Designing Safer Anilines: The Challenging Case of 4-Aminobiphenyls
Bradley Shaw2017-11-07T14:25:25+00:0070) Rationally Designing Safer Anilines: The Challenging Case of 4-Aminobiphenyls Birch, A. M.; Groombridge,
Protein–Ligand Crystal Structures Can Guide the Design of Selective Inhibitors of the FGFR Tyrosine Kinase
Bradley Shaw2017-11-07T14:23:46+00:0071) Protein–Ligand Crystal Structures Can Guide the Design of Selective Inhibitors of the FGFR
Use of Small-Molecule Crystal Structures To Address Solubility in a Novel Series of G Protein Coupled Receptor 119 Agonists: Optimization of a Lead and in Vivo Evaluation
Bradley Shaw2017-11-07T14:23:06+00:0072) Use of Small-Molecule Crystal Structures To Address Solubility in a Novel Series of
“Protein–Ligand Crystal Structures Can Guide the Design of Selective Inhibitors of the FGFR Tyrosine Kinase.”
Bradley Shaw2017-11-07T14:22:39+00:0073) “Protein–Ligand Crystal Structures Can Guide the Design of Selective Inhibitors of the FGFR
“Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes.”
Bradley Shaw2017-11-07T14:21:57+00:0074) “Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment
A System for Encoding and Searching Markush Structures
Bradley Shaw2017-11-07T14:21:31+00:0075) A System for Encoding and Searching Markush Structures Cosgrove, D. A.; Green, K.
1R,2R)-N-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly Selective Cathepsin K Inhibitor for the Treatment of Osteoarthritis
Bradley Shaw2017-11-07T14:20:59+00:0076) (1R,2R)-N-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly Selective Cathepsin K Inhibitor for the Treatment
Isosteric replacements for benzothiazoles and optimisation to potent Cathepsin K inhibitors free from hERG channel inhibition
Bradley Shaw2017-11-07T14:19:48+00:0077) Isosteric replacements for benzothiazoles and optimisation to potent Cathepsin K inhibitors free from
A matched molecular pair analysis of in vitro human microsomal metabolic stability measurements for heterocyclic replacements of di-substituted benzene containing compounds
Bradley Shaw2017-11-07T14:19:02+00:0078) A matched molecular pair analysis of in vitro human microsomal metabolic stability measurements
A matched molecular pair analysis of in-vitro human microsomal metabolic stability measurements for methylene substitution or replacements
Bradley Shaw2017-11-07T14:18:18+00:0079) A matched molecular pair analysis of in-vitro human microsomal metabolic stability measurements for
