80) Pharmacokinetic Benefits of 3,4-Dimethoxy Substitution of a Phenyl ring and Design of Isosteres

81) Identification of pyrazolo-pyrimidinones as GHS-R1a antagonists and inverse agonists for the treatment of

82) “Investigation of the Origins of Regiochemical Control in [4+2] Cycloadditions of 2-Pyrones and

83) Free-Wilson and Structural Approaches to Co-optimizing Human and Rodent Isoform Potency for 11β-Hydroxysteroid

84) Optimisation of aqueous solubility in a series of G protein coupled receptor 119

85) Design and synthesis of a novel series of cyclohexyloxy-pyridyl derivatives as inhibitors of

86) A monomeric form of iNOS can rationalise observed SAR for inhibitors of dimerisation:

87) Optimisation of biphenyl acetic acid inhibitors of diacylglycerol acetyl transferase 1 – the

88) Discovery and optimization of efficacious neutral 4-amino-6-biphenyl-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one diacylglycerol acyl transferase-1 (DGAT1) inhibitors Frederick

89) Discovery of 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an Orally Bioavailable, Potent Inhibitor of Akt Kinases Addie,